PSRLCE focuses on conducting fundamental and applied scientific research, research and development activities, and research and technology work in the following core scientific and technical directions:

1. Inorganic materials science. Development of physicochemical bases of synthesis, preparation and investigation of properties of single crystals of ternary and more complex chalcogenide, halide and chalcogenhalide compounds as promising materials for electronic equipment. Supervisor: Prof., Doctor of Chemical Sciences Barchii I.E.

2. Analytical Chemistry: New Analytical Forms Based on Chromophoric, Fluorophoric, and Electroactive Substances in Instrumental, Chemical-Sensing, and Molecular Probe Methods of Analysis and Diagnosis. Supervisor: Associate Professor, Ph.D. in Chemistry, Y.I. Studenyak.

3. Organic Chemistry: Synthesis and Study of Chemical, Physical, and Biological Properties of Novel Condensed Heterocyclic Compounds Containing N, O, S, Se, Te. Supervisor: Professor, Ph.D. in Chemistry, M.Y. Onysko.

4. Physical and Colloid Chemistry: Investigation of Oxidation Processes of n-Alkanes Using Acid-Base Catalysis. Supervisor: Associate Professor, Ph.D. in Chemistry, N.P. Holub.
5. Ecology and Environmental Protection: Development and Enhancement of Systems and Methods for Environmental Object Monitoring in the Context of Environmental Safety. Supervisor: Professor, Ph.D. in Chemistry, S.M. Sukharev.